SLC40A1 and Parkinson disease: In addition to this, mutations or knockouts of divalent metal transporter 1(DMT1), ferritin, Ferroportin (FPN), and β-amyloid precursor protein in PD animal models and human brain SN cause abnormal disturbances in iron uptake and output, leading to the formation of free radicals to promote ferroptosis to occur [34–39].