CCL20 and neoplasm: To rule out this explanation, we stratified the differential expression analysis between tumor periphery and center by MG subtype and observed similar genes downregulated in the tumor periphery in each subtype (e.g. CCL20, FCGBP; Supplementary file 5), arguing that the non-reactive phenotype is a common feature for all peripheral MG and is not only driven by a differential abundance pattern of one MG subpopulation relative to the other.