We therefore set forth to examine whether the levels of obscurin-B containing kin1 and phospho-Ser-788 N-cadherin were altered in human DCM end-stage heart failure LV samples compared with donor controls using antibodies against obscurin-kin1, phospho-Ser-788, and total N-cadherin (Figure 7). The gene discussed is CDH2; the disease is familial dilated cardiomyopathy.