As there was a decrease in Dnmt3a expression in E20 IUGR kidneys [12] and significant correlations between Dnmt3a and Kcnq1/Kcnq1ot1/Cdkn1c at E20, the DNA methylation profile of KvDMR1 was investigated. The gene discussed is KCNQ1OT1; the disease is fetal growth restriction.