In contrast, changes in Kcnq1ot1 were not sufficient to explain the decrease in the expression of another imprinted gene within the same KvDMR1 imprinting cluster, Cdkn1c, at both E20 (IUGR females) and PN1 (IUGR males and females) [12], as no correlation was found between the two genes in any group at any time point. The gene discussed is CDKN1C; the disease is fetal growth restriction.