An independent quantification of the transcript levels of ZP3-Cancer and ZP3-Oocyte in 950 overlapping CCLs confirms ZP3-Cancer is expressed at much higher levels (Supplementary Figure S1A), with a strong correlation in expression of these two transcripts between the two datasets attesting to the validity of the findings (R2 = 0.99 and 0.94 for ZP3-Cancer and ZP3-Oocyte, resp.; Supplementary Figures S1B, C). The gene discussed is ZP3; the disease is cancer.