Comparative analysis between PM and dysferlinopathy revealed that the DEGs upregulated in PM were most abundant in the protein localization to organelle pathway and helped identify four genes (KDELR3, C0PB2, TMED7, and RAB1A) that were related to ER to Golgi vesicle–mediated transport. Here, KDELR3 is linked to neuromuscular disease caused by qualitative or quantitative defects of dysferlin.