The processing of miRNAs in myeloma cells is also mediated by HNRNPA2B1, according to research by Rui Liu et al. The HNRNPA2B1-DGCR8 complex attaches to either pri-miR-92a-2-5p or pri-miR-373-3p, which promotes the maturation of miRNAs and upregulates their expression. The gene discussed is HNRNPA2B1; the disease is plasma cell myeloma.