Hence, the Tgfβ1 knockout mice (Tgfβ1−/−) were subjected to LCA injury by wire and treated with Yinxingneizhi Zhusheye (30 mg/kg/day; intraperitoneal injection) and pirfenidone capsules (72 mg/kg/day; intragastric administration) for 28 days (Figure 6(a)). This evidence concerns the gene TGFB1 and Leber congenital amaurosis.