The drug pirfenidone capsules used to treat idiopathic pulmonary fibrosis by decreasing the expression of Tgfβ1 and the drug Yinxingneizhi Zhusheye (including Ginkgolide B) were used to identify whether GB played a protective role in vascular remodeling by regulating the Tgfβ1/Smad signaling pathway. The gene discussed is TGFB1; the disease is pulmonary fibrosis.