Significantly higher serum YKL-40 concentrations on admission due to assumed macrophage involvement in the peripancreatic adipose tissue were also confirmed in a more recent study (180.5±62.01 μg/L in AP vs. 36.1±14.14 μg/L in controls, P = 0.001) (49). Here, CHI3L1 is linked to alkaline phosphatase measurement.