PKM and coronary artery disorder: This pilot study demonstrated that 1) baseline plasma PKM2 concentration was an independent predictor of ACS in CAD patients; 2) CAD patients with higher plasma PKM2 concentration had higher cumulative incidence of MACEs compared to patients with lower plasma PKM2 concentration; 3) the addition of PKM2 to a cluster of conventional risk factors significantly improved its performance for predicting the development of MACEs.