In addition, six proteins belonging to lipid metabolism (apolipoproteins D [APOD] and C3 [APOC3]), complement activation (complement C1q subcomponent subunit A [C1QA] and C5), and platelet activation pathway (glycoprotein Ib platelet subunit alpha [GP1BA] and pro‐platelet basic protein [PPBP]) were identified as biomarkers of myocardial injury in proteomics analysis of plasma‐derived EVs from patients with MI. This evidence concerns the gene C1QA and myocardial infarction.