While the precise nature of this interaction is still a subject of debate (55), it has been suggested that the NAIP/NLRC4/ASC complex formed after Salmonella infection may recruit NLRP3, potentially amplifying caspase-1 cleavage and subsequent IL-1β cytokine release (42, 54, 57). The gene discussed is NLRC4; the disease is Salmonella Infections.