Moreover, JAM3 methylation status in cervical tissues and scraping demonstrated a significant difference between low‐ and high‐grade cervical intraepithelial neoplasia (CIN) and normal cervical tissue and CIN, suggesting that JAM3 methylation could be a biomarker for the diagnosis of cervical cancer and for screening.22 Here, JAM3 is linked to cervical intraepithelial neoplasia.