FBXL6 and hepatocellular carcinoma: IHC staining results indicated that high expression of PRELID2 was consistently correlated with elevated FBXL6 (χ2 = 20.891, P < 0.001), p-ERK (χ2 = 19.535, P < 0.001), and p-mTOR (χ2 = 26.559, P < 0.001) levels in HCC tumors (Fig. 6a, b).