In 2022 no cases of malaria were documented in the Bantayan Archipelago, but eighty-nine cases of dengue fever appeared, which underscores the need for mobile dengue testing (e.g., NS1, IgG, IgM) to minimize epidemiological dissemination and warn of potential hemorrhagic fever that may require hospitalization, hourly bedside hematocrit monitoring, and intensive transfusion support. The gene discussed is CD40LG; the disease is dengue disease.