In 2022 no cases of malaria were documented in the Bantayan Archipelago, but eighty-nine cases of dengue fever appeared, which underscores the need for mobile dengue testing (e.g., NS1, IgG, IgM) to minimize epidemiological dissemination and warn of potential hemorrhagic fever that may require hospitalization, hourly bedside hematocrit monitoring, and intensive transfusion support. Here, CD40LG is linked to hemorrhagic fever.