Subsequently, 11 genes associated with sepsis diagnosis were obtained, including RETN, S100A12, IL18R1, KL, IL1RAP, GZMB, HLA-DPA1, CD3E, IL2RB, CD3G, and CCR3 (Fig. 6A, 6B, p < 0.05). The gene discussed is IL1RAP; the disease is Sepsis.