Our group recently demonstrated that ROR2 and WNT5A are significantly correlated on cytonemes of human cancer-associated fibroblasts; in the same study, ROR2 was identified in the cytoneme-receiving gastric tumour cells influencing migration of gastric cancer cells58, suggesting a conserved signalling role in vertebrate embryogenesis and disease. This evidence concerns the gene WNT5A and gastric neoplasm.