CD4 and rheumatoid arthritis: EIA patients later diagnosed with seropositive RA showed a significantly higher percentage of synovial IFNγ+CD8+ T cells compared with both the SpA (p=0.0138) and the seronegative UIA (p=0.0016) groups, and in IFNγ+CD4+ T cells compared with seronegative UIA (p=0.0089) (figure 2).