Additionally, we used RT-qPCR to confirm the CDT-induced HSP17.6 genes, which encodes a HSP related to heat-shock and seed development (Supplementary Fig. S1B), as well as CDT-suppressed PAR1 gene, encoding a PHYTOCHROME RAPIDLY REGULATED1 related to seedling development (Supplementary Fig. S1C). The gene discussed is HSP90B2P; the disease is isolated focal cortical dysplasia type II.