APOE and familial hyperaldosteronism: Next-generation sequencing (NGS) enables the identification of variants in several genes at the same time, and for FH, the optimal panel recommended is the three FH-causing genes and five FH-phenocopy genes (APOE, LDLRAP1, LIPA, ABCG5, and ABCG8) (3), which are associated to other disorders that present a similar phenotype as FH.