After cascade screening, by the end of December 2021, we have genetically identified a total of 1,000 individuals with FH: 989 with heterozygous FH and 11 with homozygous FH (three true homozygous, seven compound heterozygous, and one LDLR-APOB double heterozygote). This evidence concerns the gene APOB and familial hyperaldosteronism.