Liu proposed that iTL-PSMA was the most effective parameter in the diagnosis of high-risk prostate cancer; the specificity of iTL-PSMA and iPSMA-TV was higher than the results of the present study, the sensitivity of iTL-PSMA and iPSMA-TV was lower, the sensitivity of SUVmax was higher, and the specificity was lower.35 These differences may be related to different imaging agents and the selection of cases. The gene discussed is FOLH1; the disease is Familial prostate cancer.