METTL3-mediated m6A-modified lncRNA MALAT1 can lead to PCa proliferation by activating the PI3K/AKT signaling pathway, and METTL3-mediated lncRNA PVT1 was found to regulate the miR-27b-3b/BLM signaling axis [172, 173]. Here, METTL3 is linked to posterior cortical atrophy.