RBM15 and renal cell carcinoma: Zeng et al. found that RBM15 expression was upregulated in RCC cells and tissues, where EP300/CBP-induced acetylation modification of the RBM15 promoter led to enhanced RBM15 expression and enhanced the expression and stability of CXCL11, thereby promoting macrophage infiltration and M2 polarization, leading to cancer progression in an m6A-dependent manner [221].