In many solid tumors NR4A1 is overexpressed including lung, breast, ovarian, and colon cancer, and NR4A1 is also a negative prognostic factor for patient survival (Smith et al., 2011; Lee et al., 2012; Wang et al., 2014a; Zhou et al., 2014; Delgado et al., 2016). This evidence concerns the gene NR4A1 and malignant colon neoplasm.