ITGAX and obesity disorder: In line with previous studies (43, 44), we found a significant increase in F4/80 mRNA level along with a decrease in the gene expression of CD11c in the HFD group compared to the SCD group, suggesting that HFD-induced obesity augmented macrophage infiltration, which was reversed following the supplementation of B. coagulans T4 and L. paracasei TD3, suggesting that these probiotics attenuated inflammation in the skeletal muscle tissue.