This finding is consistent with a previous study, which has reported that increased ectopic expression of miR-34c-5p in MDA-MB-231, MDA-MB-468, and BT-549 breast cancer cells induces cell cycle arrest in G2/M phase and decreased CCND1, CDK4, and CDK6 gene expression (22). This evidence concerns the gene CCND1 and breast carcinoma.