PAIP2B and pancreatic adenocarcinoma: In order to investigate whetherPAIP2Bexpression play a crucial regulatory role in tumor microenvironment (TME), we explored the correlation betweenPAIP2Band TIICs base on the TCGA-PAAD cohort by the CIBERSORT algorithm (Fig. 3A).12We divided the patients into two groups based on PAIP2B levels and analyzed the differences in immune cell infiltration between the two groups.