In order to investigate whetherPAIP2Bexpression play a crucial regulatory role in tumor microenvironment (TME), we explored the correlation betweenPAIP2Band TIICs base on the TCGA-PAAD cohort by the CIBERSORT algorithm (Fig. 3A).12We divided the patients into two groups based on PAIP2B levels and analyzed the differences in immune cell infiltration between the two groups. The gene discussed is PAIP2B; the disease is neoplasm.