KMT2A and acute lymphoblastic leukemia: These data also supported a role of DUX4 in DUX4-rearranged ALL, ZNF384 and GATA3 in ZNF384-rearranged ALL, and HOXA9 and MEIS1 in KMT2A-rearranged ALL in the generation of subtype-specific chromatin landscapes (Figures 5C and S11).