To further evaluate subtype-enriched DASs, we determined whether they displayed enrichment patterns that were consistent with five established human B-ALL cell lines (697 = TCF3::PBX1, JIH5 = ZNF384-rearranged, Nalm6 = DUX4-rearranged, REH = ETV6::RUNX1, SEM = KMT2A-rearranged, and SUPB15 = BCR::ABL1). Here, RUNX1 is linked to precursor B-cell acute lymphoblastic leukemia.