AR and posterior cortical atrophy: We treated AR‐positive LNCaP and 22Rv1 human PCa cell lines with EPI001 (EPI) and enzalutamide (ENZ), IC50 of EPI for LNCaP and 22Rv1 was 0.48 and 0.38 μM, IC50 of ENZ for LNCaP was 0.57 μM but 22Rv1 is resistant to ENZ (Figure 1A).