According to the diagnostic criteria of the American Association for the Study of Liver Diseases, if the AFP level is highly elevated in a large tumor within a cirrhotic liver that exhibits arterial enhancement followed by venous washout on contrast-enhanced CT or magnetic resonance imaging (MRI), HCC can be identified and routine biopsy is not recommended.[21] This patient had a high AFP level, and contrast-enhanced CT showed a typical pattern of arterial uptake and washout in the venous phase. Here, AFP is linked to neoplasm.