GPT and neoplasm: Indirect liver injury is commonly seen in tumor patients who receive targeted immunotherapy, and the drugs can induce or worsen the underlying liver diseases by altering the immune function of the body.[5] Most acute DILI patients do not show any obvious symptoms, only the increased levels of liver biochemical indicators such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, and gltamyltranspeptidase in serum to varying degrees.