Online dataset analysis of the GEPIA database (http://gepia.cancer-pku.cn/index.html) indicated that the expression level of DPY30 was higher in colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ) than in healthy tissues (P < 0.05) (Fig. 1A, left). This evidence concerns the gene DPY30 and rectum adenocarcinoma.