China’s Guidelines for the Prevention and Treatment of Diabetic Nephropathy (2021 edition) [5] propose that the ratio of urinary albumin to creatinine (UACR) or 24-h urinary albumin excretion rate (UAER), estimated glomerular filtration rate (eGFR) and renal biopsy can be used for the diagnosis of DKD. This evidence concerns the gene ALB and diabetic kidney disease.