IL10 and fungal lung infectious disease: Meanwhile, Seagal et al. [15] emphasized that the pathogenicity of Cryptococcus in IL-10-/- mice was weakened, and the activity of monocyte derived DC, T cells, alveolar macrophages, etc. involved in clearing pulmonary Cryptococcus was enhanced in the lungs, indicating the therapeutic potential of IL-10 blockade in the treatment of fungal pulmonary infections.