Univariate logistic regression analysis showed that the ORs for CHD risk and severity were positively associated with PCSK9 levels (CHD group vs. non–CHD group: OR = 3.308, 95% CI: 2.137–5.121, p < 0.001; three vessel disease group vs. one vessel disease group: OR = 6.290, 95% CI: 3.349–11.814, p < 0.001; high GS group vs. low GS group: OR = 5.889, 95% CI: 3.504–9.899, p < 0.001) (Fig. 3, A, C, E). This evidence concerns the gene PCSK9 and glycogen storage disease VI.