Based on previous research findings indicating a significant correlation between FDX1 expression and epithelial-mesenchymal transition (EMT), as well as the ability of FDX1 to promote invasion and migration of GBM cells, this study employed western blot experiments to investigate the impact of FDX1 knockdown on the expressions of E-cadherin, N-cadherin, and Vimentin. The gene discussed is FDX1; the disease is glioblastoma.