The findings indicated that glioma patients with elevated FDX1 expression exhibited a higher mortality rate, while those with lower FDX1 expression demonstrated a higher survival rate (Fig. 6N). Additionally, Fig. 6O presented the Kaplan–Meier survival curve for FDX1 in TCGA, revealing a significantly lower overall survival rate in the high expression group compared to the low expression group..Finally, ROC curve was used, and find that the AUC values of FDX1 at 1- year, 3- year and 5- year are 0.721, 0.756 and 0.746. Here, FDX1 is linked to glioma.