A one-way logistic regression analysis was performed on 16 indicators that differed between the IVIG-sensitive and IVIG-resistant groups, and significant correlations were found for 12 items: days in hospital, HB, RBC, ALB, GLB, A/G, CK, ESR, IgG, ATG16L1, BECN1, and LC3II. The 12 indicators associated with IVIG unresponsive Kawasaki disease were included in a multifactorial logistic regression analysis using forward stepwise regression, and the results showed that the expression of ESR, BECN1, and LC3II mRNA were independent risk factors for IVIG-resistant Kawasaki disease (Table 8). This evidence concerns the gene ESR1 and Kawasaki disease.