Taking the post-LRP prognosis as the dependent variable (poor prognosis = 1, good prognosis = 0), and PSA, Gleason score, T stage, lymph node metastasis, seminal vesicle invasion, preoperative SII/Ki-67 index with P < 0.05 in Table 1 as the independent variables, Logistics multivariate regression analyses were performed. The gene discussed is KLK3; the disease is metastatic malignant neoplasm in the lymph nodes.