Abbreviation: BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; ALP, alkaline phosphatase; GGT, gamma-glutamyl transferase; TBA, total bile acid; PBC, primary biliary cholangitis; CHB; chronic hepatitis B. The gene discussed is GPT; the disease is biliary liver cirrhosis.