CD4 and neoplasm: Surprisingly, both groups were not statistically different in the infiltration of most immune cells, including, NK cells, CD4+ T cells, neutrophils, B cells,Th2, and cytotoxic cells, while patients in the low-LRRS group showed a higher fraction of anti-tumor immune cells, such as CD8-naive (p < 0.05), Th17 cells (p < 0.01), and Monocyte (p < 0.001) (Fig. 9H).