Using the CPTAC RNA-seq dataset from human pancreatic cancers, we confirmed RBFOX2 transcripts from the pancreas lack the first two exons present in full length RBFOX2. Interrogating the publicly available TCGA SpliceSeq database of annotated splicing events across 33 cancer types from TCGA RNA-seq datasets38, we confirmed alternative splicing of RBFOX2 exon 10 (hg19 Exon 12 in SpliceSeq) in PDAC patients. The gene discussed is RBFOX2; the disease is familial pancreatic carcinoma.