CASP3 and neoplasm: Wang et al. developed a nanoprobe using Au nanostars, Atto655 (fluorescent dye), folic acid (for targeting), and DEVD (a peptide linker which is responsive to Caspase-3, an enzyme) for synchronized tumour-targeted photothermal therapy and monitoring of the imaging of Casp-3-responsive activity, which is considered as a self-therapy.