WNT4 and ovarian carcinoma: Kuchenbaecker and colleagues showed that WNT4 SNPs (e.g., rs3820282) are associated with an OR for overall ovarian cancer of 1.11 (P = 8 × 10−7), OR = 1.09 for the endometrioid histotype (P = 0.05), OR = 1.12 for the serous histotype (P = 6 × 10−6), and OR = 1.24 for the clear cell histotype (P = 5 × 10−4; ref. 49).