ERG and neoplasm: In the JHU cohort, a few individual probes in the FASN gene body showed significantly increased methylation in ERG-negative compared with ERG-positive cases (P < 0.05, Fig. 4C), and the median across the tumor samples’ mean beta values was numerically, though not statistically significantly, higher for ERG-negative compared with ERG-positive cases (Fig. 4D).