More importantly, we identified the communication effects of chemokines, such as CXCL14-CXCR4 and CXCL12-CXCR4, and T cell cytokine, such as TGFβ1-AR, EGFR-TGFβ1 and TGFβ1-TGFβR3 were increased in AAA. The gene discussed is CXCL12; the disease is triple-A syndrome.