These genes including GSDMB, GSDMD, NLRP3, PLCG1, TNF, IL-1β and SCAF11 were significantly associated with the incidence of AAA, and the AUC according to the ROC curve was from 0.0.729 to 0.818 (Supplementary Figure 3C–3I), which suggests these genes had a highly predictive value. This evidence concerns the gene PLCG1 and triple-A syndrome.