TNF and rheumatoid arthritis: The telomerase activity in RA-FLSs declined from 29.2 to 15.7 pg/mL by TNF-α, which was markedly amplified to 18.1 and 24.6 IU/L by 10 and 20 nM PNX-20, respectively (Figure 5), implying an activation property of PNX-20 on telomerase activity in TNF-α-treated RA-FLSs.