YTHDF1 and acute myeloid leukemia: For instance, it's been reported that METTL3 partners with YTHDF1 to boost hepatocellular carcinoma progression,34 triggers the PI3K/AKT signaling pathway to enhance prostate cancer growth,35 and plays roles in chemoresistance across various cancers like oral cancer,36 acute myeloid leukemia,37 and more.