Expression patterns of LYPLAL1-DT in a nontumoral mammary epithelial cell line MCF10A and a number of breast cancer cell lines were explored using RT-qPCR, and the result disclosed that LYPLAL1-DT expression was noticeably reduced in a host of TNBC cell lines, especially BT-549 and MDA-MB-231, comparing to that in MCF10A and a series of non-TNBC cell lines (Fig. 2A), which was consistent with the results in nontumoral and TNBC samples and tissues. Here, LYPLAL1 is linked to breast cancer.