Mutations in these genes lead to unique clinical diseases related to their specific distribution: kidney stones (SLC26A1), maldevelopment (SLC26A2), congenital chloride diarrhea (SLC26A3), Pendred syndrome and goiter (SLC26A4), deafness (SLC26A5), and male infertility (SLC26A3, SLC26A8) (Dawson & Markovich, 2005; El Khouri & Touré, 2014; Everett & Green, 1999). This evidence concerns the gene SLC26A3 and goiter.