SEMA3E and inflammation: This study found that the expression of Sema3E in the vagal ganglion of EB mice was significantly higher than that in AS mice, and increased significantly in two mice models compared with the NS group, while the expression of Sema3E was downregulated after DXM treatment, suggesting Sema3E in the vagal ganglion is related to AHR and eosinophilic inflammation.