The SIRPα expression levels on CD14+ monocytes (47112 ± 20060), CD56+ NK cells (6332 ± 3348), CD3+ T cells (1166 ± 785) and CD19+ B cells (1308 ± 813) in PBC patients were statistically different (F=33.367, P<0.001). This evidence concerns the gene SIRPA and primary biliary cholangitis.