The expression levels of CD47 on CD14+ monocytes (81484 ± 31179), CD56+ NK cells (28982 ± 10467), CD3+ T cells (25124 ± 7565) and CD19+ B cells (22639 ± 5596) in PBC patients were statistically different (F=24.705, P<0.001). The gene discussed is CD19; the disease is primary biliary cholangitis.